Finding mechanistic
clues in data
Disease and trait signature gene discovery, multi-omics integration, diagnostic, prognostic and subtyping models, and independent cohort validation.
Take analysis further,
and ground every finding.
Connecting public data, multi-omics evidence and biological mechanism around your scientific question.
Finding mechanistic
Turning scattered data
into knowledge
Species-, disease- and topic-specific databases, knowledge graphs, and visual query and online analysis platforms.
From molecular interactions
to drug possibilities
Drug prediction, batch molecular docking, virtual screening and molecular dynamics, giving computational support to target and candidate molecule research.
One complete line of research.
Ordered as the first five items of the catalogue's "disease/trait signature genes & mechanisms"; each step can also stand alone.
Screen signature genes
Combine transcriptome, proteome and metabolome data to find genes tied to a disease or trait.
Related servicesBuild models
Diagnostic, prognostic or subtyping models from the signature genes.
Related servicesResolve mechanisms
Use single-cell data to see in which cells and processes the signature genes act.
Related servicesPredict drugs
CMap / LINCS to look for drugs that may reverse the disease expression signature.
Related servicesValidate externally
Test the conclusions in independent cohorts or experimental data.
Related services
Public data is a starting point too.
Without new sequencing, data can be downloaded from public databases and reanalysed to find new questions.
See public data mining services- SRARaw sequencing data download and reanalysis
- GEOArray and sequencing expression data mining
- TCGAPan-cancer multi-omics data mining
- GTExNormal-tissue expression data mining
- ENCODEEpigenomic data integration
- GEO scRNA-seqPublic single-cell data mining
Databases and platforms that can be built
15 kinds of topic databases and online platforms in the catalogue. Select any one to start a research brief.
The full research support catalogue
Specialized databases, disease/trait mechanisms and single-cell integration: 53 services in total.